Novahue Skin*

Product | Clinical Studies

Discover how comprehensive clinical trials lead to the creation of this supplement and find out what it can do for your patients.

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This product will not be available to ship until 7/1/2015
  • – Protects the skin from DNA damage due to sun exposure*
  • – Helps maintain the skin’s ability to protect against photoaging*
  • – Increases skin smoothness, density, and thickness*
  • – Helps prevent damage caused by sunlight*

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Clinical Studies

Lycopene, Phytoene, and Phytofluene Study

The effect of these three potent carotenoids on UV light and oxidative stress

Lycopene is an antioxidant capable of hindering the effects of reactive oxygen species (ROS).1 It accumulates and metabolizes in the skin, providing a first line of defense against damaging UV light.2-4 Research on the combination of lycopene, phytoene, and phytofluene has shown that these carotenoids exhibit protective action across a broader range of UV light, including UV-A and UV-B wavelengths. In a simulated solar UV light study, this particular combination was found to be more effective at lowering oxidative stress and protecting against photo-damage than lycopene alone.5
The protective effects of lycopene increase when it is combined with other carotenoids.

Clinical Study Prostate Chart

The effects of combining carnosic acid with carotenoids

When combined with these phytonutrients, carnosic acid works to support protective intracellular mechanisms, and provides antioxidant enzyme activity. It also aids in the reduction of ROS and protects against UV light.6


1. Stahl, W. et al., Dietary tomato paste protects against ultraviolet light-induced erythema in humans.J Nutr. 131:1449-1451.
2. Stahl, W. et al., 2006. Lycopene-rich products and dietary photoprotection. Photochem Photobiol Sci. 5:238-242.
3. Stahl, W. et al., 2003. Antioxidant activity of carotenoids. Molecular Aspects of Medicine. 24:345-351.
4. Lopes, et al., 2010. Natural lycopene protects melanin-producing cells from UV-induced DNA damage. J Pharm Sci. 99:1346-1357.
5. Aust, O. et al., 2005. Supplementation with tomato-based products increases lycopene, phytofluene, and phytoene levels in human serum and protects against UV-light-induced erythema. Int J Vitam Nutr Res. 75:54-60.
6. Park M. 2013. Carnosic acid, a phenolic dipertene from rosemay, prevents UV-induced expression of
matrix metalloproteinases in human skin fibroblasts and keratinocytes. Exp Dermatol. 22:336-41.

Lycopene, Phytoene, and Phytofluene Study Continued

The Benefits Of Standardized Tomato Extract

During a twelve-week study measuring the density, thickness, and smoothness of skin, statistically significant improvements were found in subjects who received the skin-grade tomato extract as opposed to a Placebo.7

Clinical Study Prostate Chart

7. Heinrich, U et al., 2006. Antioxidant supplements improve parameters related to skin structure in humans. Skin Pharmacol. Physiol. 19:224-31.

The statements on this site have not been evaluated by the FDA. Our products are not intended to diagnose, treat, cure, or prevent any disease.